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The Controlled Substances Act: schedules I–V and the Analogue Act

Explains how U.S. federal law classifies drugs into five schedules, what decides a drug's schedule, why Schedule I is different from the rest, and how the Federal Analogue Act handles designer drugs.

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I: no accepted medical use (heroin, LSD, cannabis, MDMA)
II: high abuse, severe dependence (oxycodone, fentanyl, Adderall)
III: less (ketamine, buprenorphine, steroids)
IV: low (Xanax, Valium, Ativan)
V: lowest (codeine cough syrup, ezogabine)
Weighed: medical use, abuse potential, dependence, safety. Analogue Act: look-alikes = Schedule I.
Ideally science; in reality political. DEA with HHS/FDA decides, Congress can legislate; the Federal Analogue Act (1986) covers designer drugs.

Walk through

Five schedules

Under the CSA, placement depends on accepted medical use in the U.S., relative abuse potential and likelihood of addiction — “in theory”. The full list is published every year in Title 21 C.F.R. §§ 1308.11–1308.15.

Analogy and worked example

Analogy: Schedules are like age ratings for films, except Schedule I isn't the strictest rating — it's 'not allowed in theaters at all'. II through V are all showable, with fewer restrictions as you go down; Schedule I has no legitimate showing.

Why can a doctor prescribe cocaine (for some surgical procedures) but not psilocybin, even though many people would rate cocaine as riskier?

  1. Cocaine is Schedule II: high abuse potential but an accepted medical use (topical anesthetic).

Tip: the ← and → keys move through the lesson.

Full lesson: History and reasoning about drug effects

While on: Walk through

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